Lyophilizer Freeze Dryer

Freeze Drying is the process of removing the moisture from a biological product while maintaining the integrity of the biological products, chemical structure and activities. Freeze Drying technology is used in particular for removal of moisture from the products usually of biological origin without causing any noticeable change in the original characteristics. Freeze Drying is also the preferred process in the field of Pharmacy, Chemistry and in conservation of Food.

ADVANTAGE OF FREEZE DRYING

     Heat sensitive biological materials may be freeze-dried without affecting their potency. The dried materials may be stored for years at room temperature without loss of their original characteristics.

     The freeze-dried material may be transported and shipped in small containers, and no provision is necessary for refrigeration enroute.

     Bacterial growth and enzyme action do not take place in freeze-dried products and proteins do not coagulate.

     Oxidation of many materials such as haemoglobin and vaccines are completely prevented when crying and sealing is done under high vacuum.

OPERATING PRINCIPLE:

     Flasks, ampules or vials are individually attached to the ports of a manifold or drying chamber. The product is either frozen in a freezer, by direct submersion in a low temperature bath, or by shell freezing, depending on the nature of the product and the volume to be freeze dried. The pre-frozen product is quickly attached to the drying chamber or manifold to prevent warming. The vacuum must be created in the product container quickly, and the operator relies on evaporative cooling to maintain the low temperature of the product.